Synthesis, structure-activity relationships, metabolism of the following drugs: agonists-antagonists of acetylcholine and norepinefrine receptors, acetylcolinesterase inhibitors, antiallergics, volatile and local anesthetics, sedative-hypnotics, antiepileptics, opioid analgesics, neuroleptics and anxiolitic agents, central nervous system stimulants, antiparkinson agents, diuretics, cardiac agents, antihypertensives, anticoagulants, antilipidemics, insulin and oral antidiabetics.