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B016909 - GENERAL PATHOLOGY
Main information
Teaching Language
Suggested readings
Teaching Methods
Type of Assessment
Course program
Academic Year 2017-18
Course year
Second year - Second Semester
Belonging Department
Experimantal and Clinical Medicine
Course Type
Single education field course
Scientific Area
MED/04 - EXPERIMENTAL MEDICINE AND PATHOPHYSIOLOGY
Credits
6
Teaching Hours
48
Teaching Term
01/03/2018 ⇒ 30/04/2019
Attendance required
No
Type of Evaluation
Final Grade
Course program
show
Lectureship
Teaching Language
Italian
Suggested readings (Search our library's catalogue)
Robbins &Cotran. Le basi patologiche delle malattie (Elsevier); Majno&Joris. Cellule, Tessuti e Malattia (CEA); Spector&Axford; Introduzione alla Patologia Generale (Casa Editrice Ambrosiana - CEA) o testi analoghi adatti a CdL nelle Professioni Sanitarie.
Teaching Methods
Lectures
Type of Assessment
Written examination (multiple choice and tue-false tests)
Course program
GENERAL PATHOLOGY
- Health and disease. Classification of causes of disease. Etiology, pathogenesis and pathogen. Homeostasis. Denomination of biomedical disciplines dealing with etio-pathogenesis, diagnosis and therapy.
- Elementary pathological processes.
- Inflammation: general concepts. Toxicity and persistence within tissue of pathogen and their relationship to the type of inflammatory response. General characters of acute inflammation.
- Pathophysiology of microcirculation.
- Microvascular changes in acute inflammation.
- Mediators of acute inflammation.
- Cells of acute inflammation; recruitment and action.
- Abscess and “chronic” abscess.
- Chronicized/chronic diffuse (secondary or primary, “aspecific”) inflammation and chronic granulomatous (primary, “specific”) inflammation.
- Mononuclear phagocyte system. Properties and functions of macrophages. Macrophage activation.
- Granulomas.
- Relationship between inflammation and tissue repair.
- Tissue repair and wound healing.
- Systemic effects of inflammation.
- Pathophysiology of thermoregulation.
- Hyperthermia and fever.
- Hypoxia, ischemia, shock.
- Hemostasis: platelet aggregation, plasma coagulation and fibrinolisis.
- General aspects of tumor growth. Etiology of neoplasias. Benign and malignant neoplasias. Carcinomas in situ. Local invasiveness and metastasis. General denomination of neoplasias.
- General concepts of clonogenic, stem, progenitor, precursor, differentiated and mature cell.
- Health and disease. Classification of causes of disease. Etiology, pathogenesis and pathogen. Homeostasis. Denomination of biomedical disciplines dealing with etio-pathogenesis, diagnosis and therapy.
- Elementary pathological processes.
- Inflammation: general concepts. Toxicity and persistence within tissue of pathogen and their relationship to the type of inflammatory response. General characters of acute inflammation.
- Pathophysiology of microcirculation.
- Microvascular changes in acute inflammation.
- Mediators of acute inflammation.
- Cells of acute inflammation; recruitment and action.
- Abscess and “chronic” abscess.
- Chronicized/chronic diffuse (secondary or primary, “aspecific”) inflammation and chronic granulomatous (primary, “specific”) inflammation.
- Mononuclear phagocyte system. Properties and functions of macrophages. Macrophage activation.
- Granulomas.
- Relationship between inflammation and tissue repair.
- Tissue repair and wound healing.
- Systemic effects of inflammation.
- Pathophysiology of thermoregulation.
- Hyperthermia and fever.
- Hypoxia, ischemia, shock.
- Hemostasis: platelet aggregation, plasma coagulation and fibrinolisis.
- General aspects of tumor growth. Etiology of neoplasias. Benign and malignant neoplasias. Carcinomas in situ. Local invasiveness and metastasis. General denomination of neoplasias.
- General concepts of clonogenic, stem, progenitor, precursor, differentiated and mature cell.