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B017006 - Biotechnologies of reproductive medicine
Main information
Teaching Language
Course Content
Suggested readings
Learning Objectives
Further information
Type of Assessment
Course program
Academic Year 2017-18
Course year
Second year - First Semester
Belonging Department
Biomedical, Experimental and Clinical Sciences "Mario Serio"
Modulo di sola Frequenza of
Scientific Area
MED/13 - ENDOCRINOLOGY AND METABOLISM
Credits
3
Teaching Hours
24
Teaching Term
02/10/2017 ⇒ 30/04/2019
Attendance required
No
Type of Evaluation
Giudizio Finale
Course Content
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Course program
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Lectureship
Teaching Language
Italian
Course Content
The course will focus on the pathophysiology of male and female infertility and on assisted reproductive techniques. In particular, the endocrinological, genetic/epigenetic, immunological aspects of couple infertility and the role of environmental factors (obesity, xenoestrogens) on testicular function will be discussed. Detailed insights into some diagnostic tests, such as semen analysis and routine genetic tests will be provided.
(endocrinology, biology, molecular genetics, spermatology)
(endocrinology, biology, molecular genetics, spermatology)
Suggested readings (Search our library's catalogue)
EAA/EMQN Guidelines (free access)
Krausz et al (2014) EAA/EMQN best practice guidelines for molecular diagnosis
of Y-chromosomal microdeletions: state-of-the-art 2013; Andrology, 2014, 2, 5–19;
Krausz et al (2014) EAA/EMQN best practice guidelines for molecular diagnosis
of Y-chromosomal microdeletions: state-of-the-art 2013; Andrology, 2014, 2, 5–19;
Learning Objectives
to acquire basic knowledge in Reproductive Medicine, with specific focus on endocrine and genetic aspects of tesicular and ovarian functions. To acquite basic knowledge on assisted reproductive techniques and related laboratory tests/analyses.
Further information
contact directly Prof Krausz by email: csilla.krausz@unifi.it
Type of Assessment
written exam
Course program
- Classification of male infertility
- Physiopathology of male reproductive function: endocrine aspects
- Physiopathology of female reproductive function
-Genetic causes of male infertililty: Y chromosome-linked anomalies
- Genetic causes of male infertililty: the role of CNVs and the study of exome
-Genetic causes of central hypogonadism
-Spermatogenesis and interpretation of semen analysis
- Sperm analysis: technical aspects and quality control
-Sperm capaciation and moility analysis
-in vitro spermatogenesis
-Assisted Reproductive techniques and PGD
-Immunological mechanisms of pregnancy
- Epigenetics and Assisted Reproduction
-Testicular Dysgenesis Syndrome
-Aging male gamete
-Obesity and reproduction
- Physiopathology of male reproductive function: endocrine aspects
- Physiopathology of female reproductive function
-Genetic causes of male infertililty: Y chromosome-linked anomalies
- Genetic causes of male infertililty: the role of CNVs and the study of exome
-Genetic causes of central hypogonadism
-Spermatogenesis and interpretation of semen analysis
- Sperm analysis: technical aspects and quality control
-Sperm capaciation and moility analysis
-in vitro spermatogenesis
-Assisted Reproductive techniques and PGD
-Immunological mechanisms of pregnancy
- Epigenetics and Assisted Reproduction
-Testicular Dysgenesis Syndrome
-Aging male gamete
-Obesity and reproduction