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B021416 - HEMATOLOGICAL PATHOLOGY AND DIAGNOSTICS
Main information
Teaching Language
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Further information
Type of Assessment
Course program
Academic Year 2019-20
Course year
Third year - First Semester
Belonging Department
Experimantal and Clinical Medicine
Course Type
Single education field course
Scientific Area
-
Credits
3
Teaching Hours
24
Teaching Term
30/09/2019 ⇒ 20/12/2019
Attendance required
No
Type of Evaluation
Giudizio Finale
Course program
show
Lectureship
Teaching Language
Italian
Suggested readings (Search our library's catalogue)
There is no recommended specific text, the following allow you to easily extract the necessary pathophysiology and diagnostic information:
– Castoldi G, “Core Curriculum” Ematologia, McGrawHill, 2e
– Castoldi - Liso, Malattie del sangue, McGrawHill, 6e
– Amadori, Ematologia Le basi fisiopatologiche molecolari e cliniche, Piccin 2010
– Tura, Cavo, Zinzani: Hematology. Pathphysiology, Diagnosis and Treatment. Esculapio I Edizione 2018
– Castoldi G, “Core Curriculum” Ematologia, McGrawHill, 2e
– Castoldi - Liso, Malattie del sangue, McGrawHill, 6e
– Amadori, Ematologia Le basi fisiopatologiche molecolari e cliniche, Piccin 2010
– Tura, Cavo, Zinzani: Hematology. Pathphysiology, Diagnosis and Treatment. Esculapio I Edizione 2018
Learning Objectives
The course is designed to provide the basic knowledge of anatomy and physiology, biochemistry, molecular biology and genetics of the blood and lymphatic system, in order to establish the biological basis for learning laboratory, the clinic and the principles of therapy
Prerequisites
none
Teaching Methods
Lectures and seminars
Further information
none
Type of Assessment
multiple choice test
Course program
1. Hematopoiesis. Characterization of stem cells and the hematopoietic niche. The bone marrow biopsy. Therapeutic use of stem cells
2. Blood test: interpretation of parameters. Abnormalities circulating blood cells. Leukocytosis and leukopenia, general overview. Thrombocytopenia and thrombocytosis, general overview.
3. Anemia. general framework, principles of classification. Characteristics of the main types of anemia. Principles of transfusion therapy.
4. Acute leukemia (myeloid and lymphoid). Classification of acute leukemia. Morphological , immunological, cytogenetic, molecular diagnostic approach. Principles of therapy.
5. Chronic myeloid leukemia. Clinical characteristics, diagnosis and therapy, molecular monitoring.
6. Chronic Myeloproliferative neoplasms. Clinical, molecular, principles of classification and diagnosis.
7. Lymphomas and chronic lymphoid leukemia. Clinical, molecular and principles of classification and diagnosis.
8. Monoclonal gammopathies. Clinical, molecular, principles of classification and diagnosis.
9. Thrombocytopenia. Clinical, molecular, principles of classification and diagnosis.
10. Hemophilia and other disease of coagulation system. Clinical, molecular, principles of classification and diagnosis.
11. Animal models of neoplastic blood disorders.
2. Blood test: interpretation of parameters. Abnormalities circulating blood cells. Leukocytosis and leukopenia, general overview. Thrombocytopenia and thrombocytosis, general overview.
3. Anemia. general framework, principles of classification. Characteristics of the main types of anemia. Principles of transfusion therapy.
4. Acute leukemia (myeloid and lymphoid). Classification of acute leukemia. Morphological , immunological, cytogenetic, molecular diagnostic approach. Principles of therapy.
5. Chronic myeloid leukemia. Clinical characteristics, diagnosis and therapy, molecular monitoring.
6. Chronic Myeloproliferative neoplasms. Clinical, molecular, principles of classification and diagnosis.
7. Lymphomas and chronic lymphoid leukemia. Clinical, molecular and principles of classification and diagnosis.
8. Monoclonal gammopathies. Clinical, molecular, principles of classification and diagnosis.
9. Thrombocytopenia. Clinical, molecular, principles of classification and diagnosis.
10. Hemophilia and other disease of coagulation system. Clinical, molecular, principles of classification and diagnosis.
11. Animal models of neoplastic blood disorders.