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B020185 - PHARMACOLOGY
Main information
Teaching Language
Suggested readings
Learning Objectives
Prerequisites
Teaching Methods
Further information
Type of Assessment
Course program
Sustainable Development Goals 2030
Academic Year 2022-23
Coorte 2022 - Second Cycle Degree in FOOD SCIENCE
Course year
First year - Second Semester
Belonging Department
Experimantal and Clinical Medicine
Modulo di sola Frequenza of
Scientific Area
BIO/14 - PHARMACOLOGY
Credits
6
Teaching Hours
48
Teaching Term
27/02/2023 ⇒ 16/06/2023
Attendance required
No
Type of Evaluation
Giudizio Finale
Course program
show
Lectureship
Teaching Language
Italian
Suggested readings (Search our library's catalogue)
Goodman & Gilman - The Pharmacological Basis of Therapeutics McGrow-Hill 14th ed., 2022
Learning Objectives
The didactic objective of the Pharmacology course for the Master's Degree in Food Science is to explore the basic aspects of pharmacology and therapy related to the most frequent diseases and for which the skills of future graduates will have to integrate with those of other specialists in the field of health.
Drugs representative of the most important therapeutic classes will be illustrated with regard to chemical nature, pharmacodynamic action, pharmacokinetic profile, mechanism of action, efficacy, safety, adverse reactions, contraindications, interactions with other drugs, doses and routes of administration
Drugs representative of the most important therapeutic classes will be illustrated with regard to chemical nature, pharmacodynamic action, pharmacokinetic profile, mechanism of action, efficacy, safety, adverse reactions, contraindications, interactions with other drugs, doses and routes of administration
Prerequisites
Basics of chemistry, biochemistry, physiology, general pathology and internal medicine
Teaching Methods
Lectures, self-study and in-depth analysis via platform Moodle (modular, dynamic, oriented learning environment objects)
Further information
Some in-depth lessons could be pre-recorded and discussed in the classroom or via the web
Type of Assessment
In itinere test on the acquired notions of general pharmacology and final verification with guided questions in written mode (via Moodle platform).
The student can request to take the exam in oral mode
The student can request to take the exam in oral mode
Course program
GENERAL PHARMACOLOGY Notions of Pharmacodynamics: Mechanism of action of drugs: drug targets. Agonists and antagonists, activators and inhibitory blockers. Principles of structure/activity relationship, Quantitative dose-response relationship. Therapeutic index and evaluation of the risk/benefit ratio of a drug. Adverse drug reactions. Notions of Pharmacokinetics: Routes of administration of drugs. Drug absorption, bioavailability, bioequivalence. Distribution of drugs in the body. Drug metabolism. Elimination of drugs. Individual variability of drug response and pharmacogenetics. Drug interactions. Changes in drug metabolism. Concepts of pharmacogenetics applied to general pharmacology. Notions of pharmacokinetics in the classes of patients at risk: Pregnancy, lactation, pediatric patients, geriatric patients. Drug-drug/food interactions.
SPECIAL PHARMACOLOGY:
Notions of pharmacology of the peripheral nervous system and central nervous system. Classification of drugs active on the cholinergic (parasympathetic and neuromuscular junction) and adrenergic (sympathetic) systems. Drugs active on the central nervous system: anxiolytic, hypnotic, anticonvulsant and depressant drugs in connection with the treatment of eating disorders (Bulimia and anorexia).
Pharmacology of the gastrointestinal system: Drugs for the control of gastric secretion: H2 blockers, proton pump inhibitors, antacids, role of prostagliandine. H. pylori eradication therapy. Antiemetic drugs for febrile, pregnant, postoperative and chemotherapy-induced emesis. Drugs for the control of gastro-intestinal motility. Prokinetics, laxatives, antidiarrheals.
Pharmacology of inflammation, allergic responses, autoimmune and rejection of transplanted organs: NSAIDs, Corticosteroids and immunosuppressants. Drugs for bone matrix and osteoporosis. Notions on drugs with antimicrobial and antineoplastic activity Mechanisms of resistance to antimicrobial drugs.
Drugs used in the reduction of cardiovascular risk factors: Drugs in the treatment of arterial hypertension (main classes and their association), treatment of pregnancy hypertension. Antidyslipidemic drugs. Framework of the use of drugs in the primary and secondary prevention of cardiovascular events in patients at risk; antiplatelet agents and anticoagulants; drugs of the treatment of ischemic cardiomyopathies and in cardiac arrhythmias.
Antihyperuricemic and antigottosis. Antidiabetic and anti-hyperglycemic drugs (main drugs for type 1, 2 and gestational diabetes). Antiobesity drugs and metabolic disease.
Pharmacology of the endocrine system: estrogens, progestogens, androgens and adrenocortical steroids. Contraceptives. Medications for thyroid diseases. Antianemic: Iron, folic acid, vitamin B12, Erythropoietin, white blood cell stimulating factors.
Focus on medicinal plants, their food, pharmacological use and toxicity
SPECIAL PHARMACOLOGY:
Notions of pharmacology of the peripheral nervous system and central nervous system. Classification of drugs active on the cholinergic (parasympathetic and neuromuscular junction) and adrenergic (sympathetic) systems. Drugs active on the central nervous system: anxiolytic, hypnotic, anticonvulsant and depressant drugs in connection with the treatment of eating disorders (Bulimia and anorexia).
Pharmacology of the gastrointestinal system: Drugs for the control of gastric secretion: H2 blockers, proton pump inhibitors, antacids, role of prostagliandine. H. pylori eradication therapy. Antiemetic drugs for febrile, pregnant, postoperative and chemotherapy-induced emesis. Drugs for the control of gastro-intestinal motility. Prokinetics, laxatives, antidiarrheals.
Pharmacology of inflammation, allergic responses, autoimmune and rejection of transplanted organs: NSAIDs, Corticosteroids and immunosuppressants. Drugs for bone matrix and osteoporosis. Notions on drugs with antimicrobial and antineoplastic activity Mechanisms of resistance to antimicrobial drugs.
Drugs used in the reduction of cardiovascular risk factors: Drugs in the treatment of arterial hypertension (main classes and their association), treatment of pregnancy hypertension. Antidyslipidemic drugs. Framework of the use of drugs in the primary and secondary prevention of cardiovascular events in patients at risk; antiplatelet agents and anticoagulants; drugs of the treatment of ischemic cardiomyopathies and in cardiac arrhythmias.
Antihyperuricemic and antigottosis. Antidiabetic and anti-hyperglycemic drugs (main drugs for type 1, 2 and gestational diabetes). Antiobesity drugs and metabolic disease.
Pharmacology of the endocrine system: estrogens, progestogens, androgens and adrenocortical steroids. Contraceptives. Medications for thyroid diseases. Antianemic: Iron, folic acid, vitamin B12, Erythropoietin, white blood cell stimulating factors.
Focus on medicinal plants, their food, pharmacological use and toxicity
Sustainable Development Goals 2030
Health and well-being