The course requires the knowledge of macroscopic morphology, relations, and microscopic organization, physiology and biophysics concerning the organs of the systems: circulatory (heart), urinary (kidney) as well as macroscopic and microscopic morphology of endocrine system. Knowledge include notions of pharmacological and pathological aspects of each topic to the aim of developing a clinical overall view.
The acquisition of an appropriate background of exemplifying cell, tissue, organs & system functions aim to develop the scientific and clinical attitude of students to be extended to every apparatus of human body. The understanding of the integration of physiological functions, which characterize the performance of the human body in health, will be used as a starting base to understand pathological alterations as well as the principles of drug action and the strategies of regenerative medicine.
Prerequisites
Propedeuticity
Teaching Methods
Lectures
Further information
Program and teaching materials available on didonline UNIFI
Type of Assessment
Oral examination
Course program
1. Urinary Apparatus
Morfology. General organization – kidney, renal calix and pelvis – renal circulation – the nephron.
Fisiologia. Renal function - fluid and electrolyte balance. Glomerular filtration rate and its control. Tubular function. ADH and Aldosterone. Countercurrent multiplication mechanism. Homeostatic functions (osmolarity, volume, pH and systemic pressure control). Clearance.
Pharmacology. Drugs acting on renal function: diuretics, renin–angiotensin–aldosterone system drugs, non steroidal anti inflamamtory drugs.
Nephrology . Renal pathologies- cellular and molecular basis.
2. Cardiovascular apparatus
Morfology: General organization. Heart and conduction system
Physiology: Cardiac action potential in the working myocardium and conduction system: principal currents and channels associated to cardiac action potential and pacemaker potential. Excitation-contraction coupling. Contractility and cardiac cycle. Cardiac ejection and its regulation. Regulation of cardiac function. Smooth muscle and regulation of blood flow in microcirculation. Short term regulation of blood pressure.