Ciaccio M e Lippi G. Biochimica clinica e Medicina di Laboratorio. EdiSES Università
G. Arienti. Le basi molecolari della nutrizione. Piccin
D.R. Ferrier Le basi della Biochimica. Zanichelli
Learning Objectives
At the end of the course the student will be able to give a clinical evaluation about the clinical relevance of the main laboratory tests and to have acquired knowledge on the following topics:
Laboratory Medicine: definition and aims. Clinical Biochemistry and clinical pathology as main branches of Laboratory medicine.
Routine, specialized and emergency Measures. Diagnostic protocols.
Sizes and measurement in Laboratory medicine. Analitical and biological variability. Errors. Quality control. Reference ranges. Sensibility, specificity and predictive value of a diagnostic test.
Pre-analytical and post-analytical phase in laboratory tests. Subject preparation. Sample handling and storage
Prerequisites
General Biochemistry and Physiology
Teaching Methods
Frontal lessons
Further information
Theoretical and practical ADEs of healthy cooking will be organized. Within the course, "Lessons with Experts" and with Nutritionists will alternate
Type of Assessment
Oral exam
Course program
Laboratory Medicine: definition and aims.. Analitical and biological variability.
Laboratory parameters. Sizes and Measures.
Analytic phase: sensibility, specificity, precision, accuracy in a diagnostic assay. Errors. Analitical and biological variability
Clinical phase:
Quality control. Reference ranges.Sensibility, specificity and predictive value of a diagnostic test. Plasmatic proteins assessment and alterations. Protein electrophoresis.
Plasmatic lipids and lipoproteins. Dyslipidemie.
Inflammation, myocardial infarction and heart failure markers.
Non proteic nitrogenous compounds (urea, uric acid, creatinine and bilirubin).
Clinical enzymology. Main organ/tissue function and damage markers.